HJB - Your Trusted Biologics CDMO Partner
HJB, CDMO, biologics, HJB Bio, hjbbio, China CDMO, 杭州奕安济世, Just Bio, Just biotherapeutics, HJB bio, HJB China, Hangzhou HJB
DAR and drug load distribution are critical quality attributes for ADCs. We offer comprehensive, high-quality assessment of DAR and drug load distribution tailored to meet our client’s specific needs. Our suite of analytical methods including UV-Vis spectroscopy, Hydrophobic interaction chromatography (HIC), RP-HPLC, and liquid chromatography coupled with electrospray ionization mass spectrometry (LC-ESI-MS). These methods enable us to accurately determine DAR and drug load distribution, meeting stringent quality standards.
Additionally, we provide advanced solutions for evaluating antigen-binding properties and activity using SPR, BLI, or ELISA platforms.
Table. Typical Analytical Methods for ADCs Process and Product Development
Agilent 1260 HPLC & Waters H-Class UPLC
Thermofisher Vanquish/ Q-Exactive UPLC-HRMS
MD i3X Plate Reader
Sciex PA800 Plus CE
Zip-Chip CE-MS Interface
Thermo 7500 Real Time PCR System
Protein Simple iCE3 iclEF
Waters Bioaccord LC-MS/ I-class UPLC
Cytiva T200 Biacore SPR
CDMO@hjbbio.com
